Tutor: Prof. Pedro José Sebastião University of Lisbon, Instituto Superior Técnico
Description will be given soon
Tutor : dr hab. Michał Bielejewski, Institute of Molecular Physics, Polish Academy of Sciences, Poznań, Poland
The word diffusion derives from the Latin word diffundere, which means "to spread out". In the most general case, diffusion is a phenomenon that refers to the net movement of an object driven by a gradient of some magnitude factor. The process has a stochastic nature, and its concept plays an important role in many areas of physics, chemistry, biology, sociology, economics, and finance, constituting a broad field for research. In natural sciences, diffusion is not limited to a given state of matter but can occur in solids, liquids, and gases. It conditions the life processes by determining the transport through membranes, cells eventually, the whole body. In chemical processes, it is often the central rule driving many reactions. In physics, it defines many transport processes for atoms, ions, or molecules. A distinguishing feature of diffusion is that it depends on particle random walk and results in mixing or mass transport without requiring directed bulk motion. The first description of the diffusion phenomena was given by Adolf Fick in 1855. Fick's laws can be used to solve for the diffusion coefficient, D. A diffusion process that obeys Fick's laws is called normal or Fickian diffusion. On the other hand, it is called anomalous diffusion or non-Fickian diffusion if the process does not follow these laws. This tutorial aims to give an overview of the wide range of applications of diffusion NMR and principles of NMR diffusometry methods that allow insight, for example, for accurate molecular size determination, in nanomedicine drug delivery, or separation of complex mixtures.
Tutor: dr Jacek Jenczyk NanoBioMedical Centre, Adam Mickiewicz University, Poznań, Poland
The aim of the workshop will be to introduce and explain the basics of chemical shift anisotropy. I will try to visualize the tensor formalism present in the CSA description and thus, in an intuitive way, show a direct relationship between the molecular orientation relative to the laboratory reference system and the position of the chemical shift δ in the NMR spectrum. Furthermore, we will discuss the physical significance of the shielding tensor geometry and confront it with the distribution of electronic charge density around the nucleus. Finally, I will try to explain what actually happens to shielding tensors under magic angle spinning conditions and how MAS influences and modulates effective shielding.
Tutors - dr Tomasz Zalewskidr Marek Kempka NanoBioMedical Centre, Adam Mickiewicz University, Poznań, Poland
The tutorial aims to introduce the basics of the NMR phenomena and procedures in the MRI lab. Classes will be divided into two parts. In the first part, some basic information about NMR and MRI will be provided, and in the next step will be shown the preparation of an MRI research scanner, ie. tuning coil, and magnetic field shimming. Moreover, 1D NMR experiments will be carried out.The second part will show the basic experiments using Fourier imaging methods with the introduction of the spin echo imaging technique. The building of k-space during MRI experiments will be shown, to highlight the significance of Fourier transform in Magnetic Resonance Imaging. Finally, the images for the object with a well-defined structure will be obtained with spin echo and gradient echo techniques.The tutorial will be carried out with the use of ICT technology and remote access to an MRI scanner at NanoBioMedical Centre in Poznan.
Tutor: tba JEOL Ltd .
JASON is state of the art NMR processing software from JEOL and fully vendor agnostic. Data from all vendors can be analysed in JASON, with tools including integration, multiplet analysis, assignment and for more advanced experiments such as relaxation and diffusion measurements. In this session I will cover how to use JASON to process and analyse NMR experiments along with producing reports. Moreover, JASON will organize a 3-month JASON coupons (for JASON Software) fot the attendees to access JASON before the conference which will be send to all participants.
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